Recent publications

2026 2025 2024 2023 2022

Zanders L, Arifaj D, Wagner JUG, Dimmeler S. Cellular Senescence, Inflammaging and Cardiovascular Disease. Immunol Rev. 2026 Jan;337(1):e70084. doi: 10.1111/imr.70084. PMID: 41546123; PMCID: PMC12811516.


Stilz KA, Leonard VE, Rodriguez Morales D, Glaser SF, Larcher V, Ruz Jurado M, Malacarne PF, Manickam N, Tombor LS, Abplanalp WT, Panthel J, Kujundzic H, Fischer A, Schmitz K, Müller OJ, Hille S, Kupatt C, Bozoglu T, Sami H, Ogris M, Procida-Kowalski T, Bartkuhn M, John D, Yekelchyk M, Schmachtel T, Rieger M, Pham MD, Krishnan J, Günther S, Brandes RP, Braun T, Zeiher AM, Wagner JUG, Dimmeler S. Endothelial ZBTB16: a molecular shield against cardiac aging. Eur Heart J. 2026 Mar 9;47(10):1186-1198. doi: 10.1093/eurheartj/ehaf1063. PMID: 41493057; PMCID: PMC13017564.


Shumliakivska M, Fischer A, Muhly-Reinholz M, Leonard VE, Rasper T, Aslan GS, Manavski Y, Wagner JUG, Meder B, Hille SS, Müller OJ, Luxán G, Dimmeler S. The long non-coding RNA Snhg15 protects the heart after myocardial infarction. J Mol Cell Cardiol. 2026 Jan;210:72-82. doi: 10.1016/j.yjmcc.2025.10.011. Epub 2025 Oct 27. PMID: 41161640.


Kawase H, Liu S, Kurz S, Bengelsdorff V, Bonnavion R, Jin YJ, Roquid KA, Cho H, Liang G, Banićević M, Shiva N, Yunes-Leites PS, Günther S, Tombor L, Dimmeler S, Looso M, Mattonet K, Wettschureck N, Müller UC, Offermanns S. Endothelial soluble APP/APLP2 promote heart repair through KIT-mediated angiogenesis. Sci Adv. 2026 May 22;12(21):eaeh0301. doi: 10.1126/sciadv.aeh0301. Epub 2026 May 22. PMID: 42172320; PMCID: PMC13196746.


von Scheidt M, Adkar SS, Krefting J, Hoermann G, Meggendorfer M, Bauer S, Mitchell S, Pugach I, Friess C, Ma A, Hao K, Steigerwald S, Wahle M, Kessler T, Schwab M, Voll F, Mokry M, Sofokleous C, Palm KCA, Bongiovanni D, Fleig J, Oldenbuettel L, Chen Z, Hecker JS, Bassermann F, Maegdefessel L, Graw M, Ruusalepp A, Hilgendorf I, Leuschner F, Sager HB, Heimlich JB, Koenig W, Cremer S, Leistner DM, Abplanalp WT, Dimmeler S, Zeiher AM, van der Laan SW, Pasterkamp G, Braun C, Jaiswal S, Kovacic JC, Kern W, Haferlach C, Mann M, Cassese S, Kastrati A, Haferlach T, Leeper NJ, Björkegren JLM, Schunkert H. Clonal haematopoiesis of indeterminate potential and mortality in coronary artery disease. Eur Heart J. 2026 Jan 24;47(4):453-469. doi: 10.1093/eurheartj/ehaf602. PMID: 40900105; PMCID: PMC12831187.


Herrle N, Malacarne PF, Warwick T, Cabrera-Orefice A, Chen Y, Gheisari M, Chatterjee S, Leisegang MS, Sarakpi T, Wionski S, Lopez M, Kader C, Teichmann T, Drekolia MK, Koch I, Keßler M, Klein S, Erhard Uschner F, Trebicka J, Brunst S, Proschak E, Günther S, Rosas-Lemus M, Baumgarten N, Klatt S, Speer T, Bibli SI, Segarra M, Acker-Palmer A, Wagner JUG, Wittig I, Dimmeler S, Schulz MH, Richards JB, Gilsbach R, T Denton T, Fleming I, Hannibal L, Brandes RP, Rezende F. The transaminase-ω-amidase pathway senses oxidative stress to control glutamine metabolism and α-ketoglutarate levels in endothelial cells. EMBO J. 2026 Feb;45(3):820-855. doi: 10.1038/s44318-025-00642-7. Epub 2025 Dec 17. PMID: 41408486; PMCID: PMC12864753.


Valasarajan C, Rasper T, Wilhelm J, Dhakad D, Kuhnert S, Seeger W, Dimmeler S, Bals R, Savai R, Yildirim AÖ, Zeiher A, Pullamsetti SS. Loss of Y Chromosome Associates With Lung and Cardiac Dysfunction in COPD. Compr Physiol. 2026 Apr;16(2):e70142. doi: 10.1002/cph4.70142. Erratum in: Compr Physiol. 2026 Apr;16(2):e70151. doi: 10.1002/cph4.70151. PMID: 41930401.


Leberzammer J, Abplanalp WT, Grikscheit K, Solomonidis EG, Glaser SF, Schuhmacher B, Merten M, Jeremijev G, Wilken-Schmitz A, Korth L, John D, Günther S, Kuenne C, Looso M, Valasarajan C, Benes V, Jung F, Niehaus V, Anton G, Stellbrink C, Römmele C, Göpel S, Pullamsetti SS, Vehreschild J, Vehreschild M, Ciesek S, Leistner DM, Zeiher AM, Dimmeler S, Cremer S. Atherosclerosis licenses for an exceeding immune response in COVID-19 disease by interferon priming in circulating myeloid cells. Cardiovasc Res. 2026 Feb 24;122(1):81-97. doi: 10.1093/cvr/cvaf268. PMID: 41389000.


Abplanalp WT, Raddatz MA, Schuhmacher B, Mas-Peiro S, Zuriaga MA, Matesanz N, Fuster JJ, Pershad Y, Vlasschaert C, Silver AJ, Farber-Eger E, Xu Y, Wells QS, Shahidi D, Fatima S, Yang X, Boruah AA, Ware A, Merten M, von Scheidt M, John D, Shumliakivska M, Muhly-Reinholz M, Vasa-Nicotera M, Guenter S, Savona MR, Lindman BR, Dimmeler S, Bick AG, Zeiher AM. Clonal hematopoiesis activates procalcific pathways in macrophages and promotes aortic valve stenosis. J Clin Invest. 2025 Nov 18;136(1):e171634. doi: 10.1172/JCI171634. PMID: 41252200; PMCID: PMC12721883.


Wagner JUG, Dimmeler S. Neurovascular interactions in the ageing heart. Nat Rev Cardiol. 2026 Aug;23(8):572-583. doi: 10.1038/s41569-026-01260-4. Epub 2026 Feb 18. PMID: 41708980.


Weyrich M, Ware A, Windschmitt J, Sarakpi T, Abplanalp WT, Dimmeler S, Speer T, Zeiher AM. Independent and Dose-Dependent Contributions of Clonal Hematopoiesis and Mosaic Loss of Y to Incident Heart Failure. Eur J Heart Fail. 2026 May 31:xuag187. doi: 10.1093/ejhf/xuag187. Epub ahead of print. PMID: 42219262.


Larcher V, Fischer A, Zhang L, Almolla O, Chiesa M, Andriani F, Wernet C, Serio S, Tombor LS, Peruzzo S, Mukherjee D, Bussani R, Zacchigna S, Adams RH, Dimmeler S, Evans SM, Cattaneo P, Guimarães-Camboa N. Leptin Receptor Fibroblasts Are Preferential Contributors to Cardiac Fibrosis. Circ Res. 2026 May 22;138(11):e327701. doi: 10.1161/CIRCRESAHA.125.327701. Epub 2026 Apr 16. PMID: 41988726; PMCID: PMC13189386.


Weyrich M, Ware A, Windschmitt J, Sarakpi T, Abplanalp WT, Dimmeler S, Speer T, Zeiher AM. Response to the letter by Tang and Liu Regarding our article „Independent and Dose-Dependent Contributions of Clonal Hematopoiesis and Mosaic Loss of Y to Incident Heart Failure“. Eur J Heart Fail. 2026 Jul 15:xuag219. doi: 10.1093/ejhf/xuag219. Epub ahead of print. PMID: 42456093.


Mirtschink P, Yuan T, Bischof C, Pham MD, Zhu C, Ware A, Mao Y, Wu M, Rogg EM, Bottermann K, Gonzalez-Gonoggia S, Berthonneche C, Gercken B, Hagag E, Strassburger K, Sossalla S, Stehr SN, Abplanalp W, Zamboni N, Martelli F, Pedrazzini T, Stoffel M, Dimmeler S, Krishnan J. Hypoxia-driven microRNA-27b underlies pathologic cardiac endoreplication in heart disease. Signal Transduct Target Ther. 2026 May 14;11(1):179. doi: 10.1038/s41392-026-02656-x. PMID: 42135278; PMCID: PMC13176343.


Winkler R, Griesler B, Sippl W, Boon RA, Dimmeler S, Wittig I, Yaspo ML, Hüttelmaier S, Bhayadia R, Heckl D, Klusmann JH. Lineage-restricted dependency on an oncofetal SNHG29-IGF2BP1 RNA axis in acute megakaryoblastic leukemia. Leukemia. 2026 Aug;40(8):1778-1787. doi: 10.1038/s41375-026-03040-y. Epub 2026 Jun 30. PMID: 42380666; PMCID: PMC13421336.


Mahavadi P, Korfei M, Müller-Ruttloff C, Ruppert C, Krauss E, Dorfmüller P, Gattenloehner S, Dimmeler S, El Agha E, Bellusci S, Herold S, Witte B, Ziebuhr J, Guenther A. RAAS antagonists dampen the SARS-CoV-2 infection in ex-vivo cultured human precision-cut lung slices. Respir Res. 2026 Jan 13;27(1):28. doi: 10.1186/s12931-025-03463-8. PMID: 41530760; PMCID: PMC12849188.


Mas-Peiro S, Dimmeler S, Zeiher AM. Relevance of Clonal Hematopoiesis in Immune Cells for Degenerative Aortic Valve Stenosis. J Am Heart Assoc. 2026 Mar 17;15(6):e044406. doi: 10.1161/JAHA.125.044406. Epub 2025 Nov 26. PMID: 41294132; PMCID: PMC13055804.


Cartura M, Aliraj B, Szymański W, Park C, Ferrario G, Rezende F, Güven B, Bleckwehl T, Sachs N, Mägdefessel L, Dimmeler S, Müller OJ, Jo H, Offermanns S, Hayat S, Brandes RP, Münch C, Graumann J, Weigert A, Fleming I, Siragusa M. Immunomodulatory endothelial cells contribute to T-cell recruitment and activation via antigen presentation on MHC II. Cardiovasc Res. 2026 Aug 26;122(12):1672-1687. doi: 10.1093/cvr/cvag137. PMID: 42366791.


Ortega JG, Nadadur RD, Kunitomi A, Kothen-Hill S, Wagner JUG, Kurtoglu SD, Kim B, Reid MM, Lu T, Washizu K, Zanders L, Chen H, Zhang Y, Ancheta S, Lichtarge S, Johnson WA, Thompson C, Phan DM, Combes AJ, Yang AC, Tadimeti N, Dimmeler S, Yamanaka S, Alexanian M, Theodoris CV. Temporal AI model predicts drivers of cell state trajectories across human aging. bioRxiv [Preprint]. 2026 Apr 1:2026.03.30.715396. doi: 10.64898/2026.03.30.715396. PMID: 41959091; PMCID: PMC13060336.


von Scheidt M, Eissa T, Krefting J, Friess C, Schwab M, Pugach I, Meyer D, Aschauer J, Chen Z, Hoermann G, Meggendorfer M, Bongiovanni D, Breucker D, Wenger K, Voll F, Graesser C, Kessler T, Sager HB, Oldenbuettel L, Dreßen M, Doppler SA, Kameric M, Seeler S, Krane M, Maegdefessel L, Hecker JS, Bassermann F, Sander M, Holdenrieder S, Hilgendorf I, Leuschner F, Adkar SS, Miller CL, Kaikkonen MU, Mokry M, Pasterkamp G, Natarajan P, Fuster JJ, Bick AG, Heimlich JB, Rieger MA, Cremer S, Dimmeler S, Zeiher AM, Abplanalp WT, Björkegren JLM, Leeper NJ, Linkohr B, Peters A, Kastrati A, Cassese S, Koenig W, Fleischmann F, Schunkert H, Žigman M. Plasma infrared molecular fingerprinting stratifies residual risk in coronary artery disease and reflects clonal haematopoiesis- associated biology. Eur Heart J. 2026 Jul 29:ehag587. doi: 10.1093/eurheartj/ehag587. Epub ahead of print. PMID: 42522903.


Yang X, Fatima S, Sampere-Birlanga S, Ware A, Shumliakivska M, Zanders L, Radhakrishnan S, Luxán G, John D, Günther S, Mas-Peiro S, Dimmeler S, Zeiher AM, Abplanalp WT. Mutation-resolved single-cell transcriptomics reveals enhanced β-amyloid clearance in TET2-mutant human monocytes. JCI Insight. 2026 Aug 24;11(16):e208804. doi: 10.1172/jci.insight.208804. PMID: 42635046; PMCID: PMC13502165.


Ruz Jurado M, Rodriguez Morales D, Zanders L, Genetzakis E, Dimmeler S, John D. DoTools: a cross platform framework to streamline common single cell workflows. Bioinform Adv. 2026 Apr 29;6(1):vbag098. doi: 10.1093/bioadv/vbag098. PMID: 42109579; PMCID: PMC13154416.

Ziegler KA, Engelhardt S, Carnevale D, McAlpine CS, Guzik TJ, Dimmeler S, Swirski FK. Neural Mechanisms in Cardiovascular Health and Disease. Circ Res. 2025 May 23;136(11):1233-1261. doi: 10.1161/CIRCRESAHA.125.325580. Epub 2025 May 22. PMID: 40403111.


Lacolley P, Mittelbrunn M, Dimmeler S. Rethinking cardiovascular ageing. Cardiovasc Res. 2025 Aug 28;121(10):1465-1467. doi: 10.1093/cvr/cvaf140. PMID: 40796193.


Hasan SS, John D, Rudnicki M, AlZaim I, Eberhard D, Moll I, Taylor J, Klein C, von Heesen M, Conradi LC, Adams RH, Lammert E, Kalucka J, Ruhrberg C, Dimmeler S, Fischer A. Obesity drives depot-specific vascular remodeling in male white adipose tissue. Nat Commun. 2025 Jun 25;16(1):5392. doi: 10.1038/s41467-025-60910-2. PMID: 40562785; PMCID: PMC12198381.


Rodriguez Morales D, Larcher V, Ruz Jurado M, Arifaj D, Tombor LS, Zanders L, Zeiher AM, Kuppe C, John D, Wagner JUG, Schulz MH, Dimmeler S. Vascular Niches Are the Primary Hotspots in Cardiac Aging. Circ Res. 2025 Nov 7;137(11):1353-1367. doi: 10.1161/CIRCRESAHA.125.327060. Epub 2025 Oct 15. PMID: 41090219; PMCID: PMC12591552.


Tombor LS, Lautenschläger T, Glaser SF, Fischer A, Merten M, Hille SS, Müller OJ, Kupatt C, Bozoglu T, Kugler C, Sami H, Ogris M, Stilz KA, Panthel J, Muhly-Reinholz M, Kettenhausen LM, Zanders L, Stein L, Kiessling P, Sicklinger F, Leuschner F, Schuhmacher B, Siragusa M, Rodriguez Morales D, John D, Kujundzic H, Katschke MT, Solomonidis EG, Luxán G, Hehlgans S, Rödel F, Kuppe C, Abplanalp WT, Cremer S, Dimmeler S. Immunoregulatory Endothelial Cells Interact With T Cells After Myocardial Infarction. Circ Res. 2025 Aug 29;137(6):866-879. doi: 10.1161/CIRCRESAHA.125.326145. Epub 2025 Jul 30. PMID: 40735785; PMCID: PMC12398352.


Liberale L, Tual-Chalot S, Sedej S, Ministrini S, Georgiopoulos G, Grunewald M, Bäck M, Bochaton-Piallat ML, Boon RA, Ramos GC, de Winther MPJ, Drosatos K, Evans PC, Ferguson JF, Forslund-Startceva SK, Goettsch C, Giacca M, Haendeler J, Kallikourdis M, Ketelhuth DFJ, Koenen RR, Lacolley P, Lutgens E, Maffia P, Miwa S, Monaco C, Montecucco F, Norata GD, Osto E, Richardson GD, Riksen NP, Soehnlein O, Spyridopoulos I, Van Linthout S, Vilahur G, Wentzel JJ, Andrés V, Badimon L, Benetos A, Binder CJ, Brandes RP, Crea F, Furman D, Gorbunova V, Guzik TJ, Hill JA, Lüscher TF, Mittelbrunn M, Nencioni A, Netea MG, Passos JF, Stamatelopoulos KS, Tavernarakis N, Ungvari Z, Wu JC, Kirkland JL, Camici GG, Dimmeler S, Kroemer G, Abdellatif M, Stellos K. Roadmap for alleviating the manifestations of ageing in the cardiovascular system. Nat Rev Cardiol. 2025 Aug;22(8):577-605. doi: 10.1038/s41569-025-01130-5. Epub 2025 Feb 19. PMID: 39972009; PMCID: PMC13383118.


Weyrich M, Windschmitt J, Abplanalp WT, Ware A, Sarakpi T, Zewinger S, Zanders L, Dimmeler S, Zeiher AM, Speer T. Loss of Y chromosome: proteomic signatures in human cardiovascular disease. Eur Heart J. 2025 Dec 22;46(48):5237-5239. doi: 10.1093/eurheartj/ehaf657. PMID: 40886062; PMCID: PMC12718684.


Shumliakivska M, Fischer A, Muhly-Reinholz M, Leonard VE, Rasper T, Aslan GS, Manavski Y, Wagner JUG, Meder B, Hille SS, Müller OJ, Luxán G, Dimmeler S. The long non-coding RNA Snhg15 protects the heart after myocardial infarction. J Mol Cell Cardiol. 2026 Jan;210:72-82. doi: 10.1016/j.yjmcc.2025.10.011. Epub 2025 Oct 27. PMID: 41161640.


Luxán G, Winkelmeier T, Bodemer C, Toğru BN, Shumliakivska M, Muhly-Reinholz M, Fischer A, Ruz Jurado M, John D, Abplanalp WT, Dimmeler S. Ageing-associated endothelial decorin induction and the impact of non-glycanated decorin on cardiac inflammation. Cardiovasc Res. 2025 Aug 28;121(10):1623-1634. doi: 10.1093/cvr/cvaf128. PMID: 40726182.


Herrle N, Malacarne PF, Warwick T, Cabrera-Orefice A, Chen Y, Gheisari M, Chatterjee S, Leisegang MS, Sarakpi T, Wionski S, Lopez M, Kader C, Teichmann T, Drekolia MK, Koch I, Keßler M, Klein S, Erhard Uschner F, Trebicka J, Brunst S, Proschak E, Günther S, Rosas-Lemus M, Baumgarten N, Klatt S, Speer T, Bibli SI, Segarra M, Acker-Palmer A, Wagner JUG, Wittig I, Dimmeler S, Schulz MH, Richards JB, Gilsbach R, T Denton T, Fleming I, Hannibal L, Brandes RP, Rezende F. The transaminase-ω-amidase pathway senses oxidative stress to control glutamine metabolism and α-ketoglutarate levels in endothelial cells. EMBO J. 2026 Feb;45(3):820-855. doi: 10.1038/s44318-025-00642-7. Epub 2025 Dec 17. PMID: 41408486; PMCID: PMC12864753.


Shao J, Kwon J, Wang T, Günther S, Tombor LS, Warwick T, Shaheryar Z, Brandes RP, Dimmeler S, Wenzel J, Offermanns S, Schwaninger M, Wettschureck N. Orphan receptor GPR153 facilitates vascular damage responses by modulating cAMP levels, YAP/TAZ signaling, and NF-κB activation. Nat Commun. 2025 Jul 7;16(1):6232. doi: 10.1038/s41467-025-61057-w. PMID: 40623996; PMCID: PMC12234975.


Manickam N, Sultan I, Panthel J, Kujundzic H, Fischer A, Schmitz K, Ruz Jurado M, Rodriguez Morales D, John D, Glaser SF, Stilz KA, Malacarne PF, Brandes RP, Braun T, Lerchenmüller C, Betge F, Abplanalp WT, Alitalo K, Dimmeler S, Wagner JUG. Beneficial effects of vascular endothelial growth factor B gene transfer in the aged heart. Cardiovasc Res. 2025 Aug 28;121(10):1594-1608. doi: 10.1093/cvr/cvaf046. PMID: 40116846; PMCID: PMC12391667.


Mukherjee D, Larcher V, Winter H, Sachs N, Andriani F, Chiesa M, Perrucci GL, Rega S, Günther S, Kuenne C, Martin JC, Gu Y, Pelisek J, Fischer A, Peruzzo S, Pizzo E, Peterson KL, Dimmeler S, Maegdefessel L, Cattaneo P, Evans SM, Guimarães-Camboa N. Transcription regulation by TBX18 in smooth muscle cells is essential for normal aortic development and homeostasis. Cardiovasc Res. 2025 Dec 9;121(15):2419-2431. doi: 10.1093/cvr/cvaf201. PMID: 41263385; PMCID: PMC12687880.


Abplanalp WT, Raddatz MA, Schuhmacher B, Mas-Peiro S, Zuriaga MA, Matesanz N, Fuster JJ, Pershad Y, Vlasschaert C, Silver AJ, Farber-Eger E, Xu Y, Wells QS, Shahidi D, Fatima S, Yang X, Boruah AA, Ware A, Merten M, von Scheidt M, John D, Shumliakivska M, Muhly-Reinholz M, Vasa-Nicotera M, Guenter S, Savona MR, Lindman BR, Dimmeler S, Bick AG, Zeiher AM. Clonal hematopoiesis activates procalcific pathways in macrophages and promotes aortic valve stenosis. J Clin Invest. 2025 Nov 18;136(1):e171634. doi: 10.1172/JCI171634. PMID: 41252200; PMCID: PMC12721883.


Vanicek LR, Fischer A, Ruz Jurado M, Tamiato A, Procida-Kowalski T, Wilhelm J, Hecker D, Merten M, Escher F, Kattih B, Puntmann V, John D, Schulz MH, Nagel E, Dimmeler S, Luxán G. STAT3 expression is reduced in cardiac pericytes in HFpEF and its loss reduces cellular adhesion and induces pericyte senescence. FEBS Lett. 2025 Jun;599(12):1781-1794. doi: 10.1002/1873-3468.70057. Epub 2025 May 1. PMID: 40309782; PMCID: PMC12183626.


Cremer S, von Scheidt M, Kirschbaum K, Tombor L, Mas-Peiro S, Abplanalp W, Rasper T, Ware A, Schuff A, Berkowitsch A, Krefting J, Leistner D, Schunkert H, Speer T, Dimmeler S, Zeiher AM. Prognostic significance of somatic mutations in myeloid cells of men with chronic heart failure – interaction between loss of Y chromosome and clonal haematopoiesis. Eur J Heart Fail. 2025 Dec;27(12):3219-3234. doi: 10.1002/ejhf.3778. Epub 2025 Jul 24. PMID: 40702883; PMCID: PMC12803692.


Yuan T, Wu M, Zhu C, Yu H, Pham MD, Bottermann K, Mao Y, Wang Y, Langner M, Peitzsch M, Das AP, Kauferstein S, Ward J, Mirtschink P, Zeiher AM, Dimmeler S, Krishnan J. Targeting miRNA-1a and miRNA-15b: A Novel Combinatorial Strategy to Drive Adult Cardiac Regeneration. Adv Sci (Weinh). 2025 Jun;12(21):e2414455. doi: 10.1002/advs.202414455. Epub 2025 Apr 3. PMID: 40178022; PMCID: PMC12140343.


Weyrich M, Zewinger S, Sarakpi T, Rasper T, Kleber ME, Cremer S, Zanders L, Fleck F, Siegbahn A, Wallentin L, Abplanalp WT, Nerbas L, Fay S, Eberle AL, Dimmeler S, März W, Speer T, Zeiher AM. Mosaic loss of Y chromosome and mortality after coronary angiography. Eur Heart J. 2025 May 2;46(17):1603-1616. doi: 10.1093/eurheartj/ehaf035. PMID: 39935193; PMCID: PMC12046225.


Boeckling F, Rasper T, Zanders L, Pergola G, Cremer S, Mas-Peiro S, Vasa-Nicotera M, Leistner D, Dimmeler S, Kattih B. Extracellular Matrix Proteins Improve Risk Prediction in Patients Undergoing Transcatheter Aortic Valve Replacement. J Am Heart Assoc. 2025 Mar 4;14(5):e037296. doi: 10.1161/JAHA.124.037296. Epub 2025 Feb 26. PMID: 40008512; PMCID: PMC12132695.


Northoff BH, Herbst A, Wenk C, Weindl L, Gäbel G, Brezski A, Zarnack K, Küpper A, Dimmeler S, Moretti A, Laugwitz KL, Engelhardt S, Maegdefessel L, Boon RA, Doppler S, Dreßen M, Lahm H, Lange R, Krane M, Krohn K, Kohlmaier A, Holdt LM, Teupser D. Circular RNAs increase during vascular cell differentiation and are biomarkers for vascular disease. Cardiovasc Res. 2025 Apr 29;121(3):405-423. doi: 10.1093/cvr/cvaf013. PMID: 39901821; PMCID: PMC12038242.


Mas-Peiro S, Dimmeler S, Zeiher AM. Relevance of Clonal Hematopoiesis in Immune Cells for Degenerative Aortic Valve Stenosis. J Am Heart Assoc. 2026 Mar 17;15(6):e044406. doi: 10.1161/JAHA.125.044406. Epub 2025 Nov 26. PMID: 41294132; PMCID: PMC13055804.


Kumar Maji R, Fischer A, Rogg EM, Möller M, Gasparoni G, Simon M, Dimmeler S, Schulz MH. A cell type-specific expression atlas of small and total RNA in the heart after myocardial infarction. Sci Data. 2025 May 19;12(1):816. doi: 10.1038/s41597-025-05061-1. PMID: 40389446; PMCID: PMC12089340.


Kattih B, Fischer A, Muhly-Reinholz M, Tombor L, Nicin L, Cremer S, Zeiher AM, John D, Abplanalp WT, Dimmeler S. Inhibition of miR-92a normalizes vascular gene expression and prevents diastolic dysfunction in heart failure with preserved ejection fraction. J Mol Cell Cardiol. 2025 Jan;198:89-98. doi: 10.1016/j.yjmcc.2024.11.004. Epub 2024 Nov 24. PMID: 39592091.


Ruz Jurado M, Rodriguez Morales D, Genetzakis E, Ardakani FB, Zanders L, Fischer A, Buettner F, Schulz MH, Dimmeler S, John D. Decoding heart failure subtypes with neural networks via differential explanation analysis. Brief Bioinform. 2025 Nov 1;26(6):bbaf581. doi: 10.1093/bib/bbaf581. PMID: 41222558; PMCID: PMC12610404.


Dimmeler S, Ferri L, Nioi P, O’Donnell CJ, Damy T, Gómez-Outes A, Giacca M, Guo W, Kavousi M, Kupatt C, Landmesser U, Schunkert H, Zouridakis E, Elliott PM. Translation of genomics into routine cardiological practice: insights from a European Society of Cardiology Cardiovascular Round Table. Eur Heart J. 2025 Apr 15;46(15):1384-1393. doi: 10.1093/eurheartj/ehaf041. PMID: 39969133.

Trogisch FA, Abouissa A, Keles M, Birke A, Fuhrmann M, Dittrich GM, Weinzierl N, Wink E, Cordero J, Elsherbiny A, Martin-Garrido A, Grein S, Hemanna S, Hofmann E, Nicin L, Bibli SI, Airik R, Kispert A, Kist R, Quanchao S, Kürschner SW, Winkler M, Gretz N, Mogler C, Korff T, Koch PS, Dimmeler S, Dobreva G, Heineke J. Endothelial cells drive organ fibrosis in mice by inducing expression of the transcription factor SOX9. Sci Transl Med. 2024 Feb 28;16(736):eabq4581. doi: 10.1126/scitranslmed.abq4581. Epub 2024 Feb 28. PMID: 38416842.


Lyu YX, Fu Q, Wilczok D, Ying K, King A, Antebi A, Vojta A, Stolzing A, Moskalev A, Georgievskaya A, Maier AB, Olsen A, Groth A, Simon AK, Brunet A, Jamil A, Kulaga A, Bhatti A, Yaden B, Pedersen BK, Schumacher B, Djordjevic B, Kennedy B, Chen C, Huang CY, Correll CU, Murphy CT, Ewald CY, Chen D, Valenzano DR, Sołdacki D, Erritzoe D, Meyer D, Sinclair DA, Chini EN, Teeling EC, Morgen E, Verdin E, Vernet E, Pinilla E, Fang EF, Bischof E, Mercken EM, Finger F, Kuipers F, Pun FW, Gyülveszi G, Civiletto G, Zmudze G, Blander G, Pincus HA, McClure J, Kirkland JL, Peyer J, Justice JN, Vijg J, Gruhn JR, McLaughlin J, Mannick J, Passos J, Baur JA, Betts-LaCroix J, Sedivy JM, Speakman JR, Shlain J, von Maltzahn J, Andreasson KI, Moody K, Palikaras K, Fortney K, Niedernhofer LJ, Rasmussen LJ, Veenhoff LM, Melton L, Ferrucci L, Quarta M, Koval M, Marinova M, Hamalainen M, Unfried M, Ringel MS, Filipovic M, Topors M, Mitin N, Roy N, Pintar N, Barzilai N, Binetti P, Singh P, Kohlhaas P, Robbins PD, Rubin P, Fedichev PO, Kamya P, Muñoz-Canoves P, de Cabo R, Faragher RGA, Konrad R, Ripa R, Mansukhani R, Büttner S, Wickström SA, Brunemeier S, Jakimov S, Luo S, Rosenzweig-Lipson S, Tsai SY, Dimmeler S, Rando TA, Peterson TR, Woods T, Wyss-Coray T, Finkel T, Strauss T, Gladyshev VN, Longo VD, Dwaraka VB, Gorbunova V, Acosta-Rodríguez VA, Sorrentino V, Sebastiano V, Li W, Suh Y, Zhavoronkov A, Scheibye-Knudsen M, Bakula D. Longevity biotechnology: bridging AI, biomarkers, geroscience and clinical applications for healthy longevity. Aging (Albany NY). 2024 Oct 16;16(20):12955-12976. doi: 10.18632/aging.206135. Epub 2024 Oct 16. PMID: 39418098; PMCID: PMC11552646.


Tamiato A, Tombor LS, Fischer A, Muhly-Reinholz M, Vanicek LR, Toğru BN, Neitz J, Glaser SF, Merten M, Rodriguez Morales D, Kwon J, Klatt S, Schumacher B, Günther S, Abplanalp WT, John D, Fleming I, Wettschureck N, Dimmeler S, Luxán G. Age-Dependent RGS5 Loss in Pericytes Induces Cardiac Dysfunction and Fibrosis. Circ Res. 2024 May 10;134(10):1240-1255. doi: 10.1161/CIRCRESAHA.123.324183. Epub 2024 Apr 2. PMID: 38563133; PMCID: PMC11081481.


Dimmeler S, Zeiher A. Herz und Blut: klonale Hämatopoese [Heart and blood: clonal hematopoiesis]. Herz. 2024 Mar;49(2):105-110. German. doi:

10.1007/s00059-024-05237-2. Epub 2024 Feb 29. PMID: 38424288.


Zhang Q, Yaoita N, Tabuchi A, Liu S, Chen SH, Li Q, Hegemann N, Li C, Rodor J, Timm S, Laban H, Finkel T, Stevens T, Alvarez DF, Erfinanda L, de Perrot M, Kucherenko MM, Knosalla C, Ochs M, Dimmeler S, Korff T, Verma S, Baker AH, Kuebler WM. Endothelial Heterogeneity in the Response to Autophagy Drives Small Vessel Muscularization in Pulmonary Hypertension. Circulation. 2024 Aug 6;150(6):466-487. doi: 10.1161/CIRCULATIONAHA.124.068726. Epub 2024 Jun 14. PMID: 38873770.


Shumliakivska M, Luxán G, Hemmerling I, Scheller M, Li X, Müller-Tidow C, Schuhmacher B, Sun Z, Dendorfer A, Debes A, Glaser SF, Muhly-Reinholz M, Kirschbaum K, Hoffmann J, Nagel E, Puntmann VO, Cremer S, Leuschner F, Abplanalp WT, John D, Zeiher AM, Dimmeler S. DNMT3A clonal hematopoiesis-driver mutations induce cardiac fibrosis by paracrine activation of fibroblasts. Nat Commun. 2024 Jan 19;15(1):606. doi: 10.1038/s41467-023-43003-w. PMID: 38242884; PMCID: PMC10799021.


Weyrich M, Cremer S, Gerster M, Sarakpi T, Rasper T, Zewinger S, Patyna SR, Leistner DM, Heine GH, Wanner C, März W, Fliser D, Dimmeler S, Zeiher AM, Speer T. Loss of Y Chromosome and Cardiovascular Events in Chronic Kidney Disease. Circulation. 2024 Sep 3;150(10):746-757. doi: 10.1161/CIRCULATIONAHA.124.069139. Epub 2024 Jul 15. PMID: 39005209; PMCID: PMC11361358.


Lozano-Vidal N, Stanicek L, Bink DI, Juni RP, Hooglugt A, Kremer V, Phelp P, van Bergen A, MacInnes AW, Dimmeler S, Boon RA. Aging-regulated PNUTS maintains endothelial barrier function via SEMA3B suppression. Commun Biol. 2024 May 7;7(1):541. doi: 10.1038/s42003-024-06230-5. PMID: 38714838; PMCID: PMC11076560.


Lin A, Brittan M, Baker AH, Dimmeler S, Fisher EA, Sluimer JC, Misra A. Clonal Expansion in Cardiovascular Pathology. JACC Basic Transl Sci. 2023 Jul 19;9(1):120-144. doi: 10.1016/j.jacbts.2023.04.008. PMID: 38362345; PMCID: PMC10864919.


Lui KO, Ma Z, Dimmeler S. SARS-CoV-2 induced vascular endothelial dysfunction: direct or indirect effects? Cardiovasc Res. 2024 Feb

27;120(1):34-43. doi: 10.1093/cvr/cvad191. PMID: 38159046.


Maegdefessel L, Boon RA, Dimmeler S. Noncoding RNAs in the Vasculature: Basic Mechanisms and Therapeutic Perspectives. Arterioscler Thromb Vasc Biol. 2024 Jan;44(1):3-6. doi: 10.1161/ATVBAHA.123.319564. Epub 2023 Dec 27. PMID: 38150514.


Kattih B, Fischer A, Muhly-Reinholz M, Tombor L, Nicin L, Cremer S, Zeiher AM, John D, Abplanalp WT, Dimmeler S. Inhibition of miR-92a normalizes vascular gene expression and prevents diastolic dysfunction in heart failure with preserved ejection fraction. J Mol Cell Cardiol. 2025 Jan;198:89-98. doi: 10.1016/j.yjmcc.2024.11.004. Epub 2024 Nov 24. PMID: 39592091.


Jurado MR, Tombor LS, Arsalan M, Holubec T, Emrich F, Walther T, Abplanalp W, Fischer A, Zeiher AM, Schulz MH, Dimmeler S, John D. Improved integration of single-cell transcriptome data demonstrates common and unique signatures of heart failure in mice and humans. Gigascience. 2024 Jan 2;13:giae011. doi: 10.1093/gigascience/giae011. PMID: 38573186; PMCID: PMC10993718.

Wagner JUG, Tombor LS, Malacarne PF, Kettenhausen LM, Panthel J, Kujundzic H, Manickam N, Schmitz K, Cipca M, Stilz KA, Fischer A, Muhly-Reinholz M, Abplanalp WT, John D, Mohanta SK, Weber C, Habenicht AJR, Buchmann GK, Angendohr S, Amin E, Scherschel K, Klöcker N, Kelm M, Schüttler D, Clauss S, Günther S, Boettger T, Braun T, Bär C, Pham MD, Krishnan J, Hille S, Müller OJ, Bozoglu T, Kupatt C, Nardini E, Osmanagic-Myers S, Meyer C, Zeiher AM, Brandes RP, Luxán G, Dimmeler S. Aging impairs the neurovascular interface in the heart. Science. 2023 Aug 25;381(6660):897-906. doi: 10.1126/science.ade4961. Epub 2023 Aug 24. PMID: 37616346.


Abplanalp WT, Schuhmacher B, Cremer S, Merten M, Shumliakivska M, Macinkovic I, Zeiher AM, John D, Dimmeler S. Cell-intrinsic effects of clonal hematopoiesis in heart failure. Nat Cardiovasc Res. 2023 Sep;2(9):819-834. doi: 10.1038/s44161-023-00322-x. Epub 2023 Sep 4. PMID: 39196061; PMCID: PMC11357996.


Hua Y, Vella G, Rambow F, Allen E, Martinez AA, Duhamel M, Takeda A, Jalkanen S, Junius S, Smeets A, Nittner D, Dimmeler S, Hehlgans T, Liston A, Bosisio FM, Floris G, Laoui D, Hollmén M, Lambrechts D, Merchiers P, Marine JC, Schlenner S, Bergers G. Cancer immunotherapies transition endothelial cells into HEVs that generate TCF1+ T lymphocyte niches through a feed-forward loop. Cancer Cell. 2023 Jan 9;41(1):226. doi: 10.1016/j.ccell.2022.12.006. Erratum for: Cancer Cell. 2022 Dec 12;40(12):1600-1618.e10. doi: 10.1016/j.ccell.2022.11.002. PMID: 36626867.


Lin A, Brittan M, Baker AH, Dimmeler S, Fisher EA, Sluimer JC, Misra A. Clonal Expansion in Cardiovascular Pathology. JACC Basic Transl Sci. 2023 Jul 19;9(1):120-144. doi: 10.1016/j.jacbts.2023.04.008. PMID: 38362345; PMCID: PMC10864919.


Gatsiou A, Tual-Chalot S, Napoli M, Ortega-Gomez A, Regen T, Badolia R, Cesarini V, Garcia-Gonzalez C, Chevre R, Ciliberti G, Silvestre-Roig C, Martini M, Hoffmann J, Hamouche R, Visker JR, Diakos N, Wietelmann A, Silvestris DA, Georgiopoulos G, Moshfegh A, Schneider A, Chen W, Guenther S, Backs J, Kwak S, Selzman CH, Stamatelopoulos K, Rose-John S, Trautwein C, Spyridopoulos I, Braun T, Waisman A, Gallo A, Drakos SG, Dimmeler S, Sperandio M, Soehnlein O, Stellos K. The RNA editor ADAR2 promotes immune cell trafficking by enhancing endothelial responses to interleukin-6 during sterile inflammation. Immunity. 2023 May 9;56(5):979-997.e11. doi: 10.1016/j.immuni.2023.03.021. Epub 2023 Apr 25. PMID: 37100060.


Rogala S, Ali T, Melissari MT, Währisch S, Schuster P, Sarre A, Emídio RC, Boettger T, Rogg EM, Kaur J, Krishnan J, Dumbović G, Dimmeler S, Ounzain S, Pedrazzini T, Herrmann BG, Grote P. The lncRNA Sweetheart regulates compensatory cardiac hypertrophy after myocardial injury in murine males. Nat Commun. 2023 Nov 2;14(1):7024. doi: 10.1038/s41467-023-42760-y. PMID: 37919291; PMCID: PMC10622434.


Kattih B, Boeckling F, Shumliakivska M, Tombor L, Rasper T, Schmitz K, Hoffmann J, Nicin L, Abplanalp WT, Carstens DC, Arsalan M, Emrich F, Holubec T, Walther T, Puntmann VO, Nagel E, John D, Zeiher AM, Dimmeler S. Single-nuclear transcriptome profiling identifies persistent fibroblast activation in hypertrophic and failing human hearts of patients with longstanding disease. Cardiovasc Res. 2023 Nov 25;119(15):2550-2562. doi: 10.1093/cvr/cvad140. PMID: 37648651.


Schierwagen R, Gu W, Brieger A, Brüne B, Ciesek S, Đikić I, Dimmeler S, Geisslinger G, Greten FR, Hermann E, Hildt E, Kempf VAJ, Klein S, Koch I, Mühl H, Müller V, Peiffer KH, Kestner RI, Piiper A, Rohde G, Scholich K, Schulz MH, Storf H, Toptan T, Vasa-Nicotera M, Vehreschild MJGT, Weigert A, Wild PJ, Zeuzem S, Engelmann C; ACLF-I Investigators,; Schaefer L, Welsch C, Trebicka J. Pathogenetic mechanisms and therapeutic approaches of acute-to-chronic liver failure. Am J Physiol Cell Physiol. 2023 Jul 1;325(1):C129-C140. doi: 10.1152/ajpcell.00101.2023. Epub 2023 Jun 5. PMID: 37273239.


von Scheidt M, Bauer S, Ma A, Hao K, Kessler T, Vilne B, Wang Y, Hodonsky CJ, Ghosh SKB, Mokry M, Gao H, Kawai K, Sakamoto A, Kaiser J, Bongiovanni D, Fleig J, Oldenbuettel L, Chen Z, Moggio A, Sager HB, Hecker JS, Bassermann F, Maegdefessel L, Miller CL, Koenig W, Zeiher AM, Dimmeler S, Graw M, Braun C, Ruusalepp A, Leeper NJ, Kovacic JC, Björkegren JLM, Schunkert H. Leukocytes carrying <i>Clonal Hematopoiesis of Indeterminate Potential</i> (CHIP) Mutations invade Human Atherosclerotic Plaques. medRxiv [Preprint]. 2023 Jul 26:2023.07.22.23292754. doi: 10.1101/2023.07.22.23292754. PMID: 37546840; PMCID: PMC10402238.


Mas-Peiro S, Abplanalp WT, Rasper T, Berkowitsch A, Leistner DM, Dimmeler S, Zeiher AM. Mosaic loss of Y chromosome in monocytes is associated with lower survival after transcatheter aortic valve replacement. Eur Heart J. 2023 Jun 1;44(21):1943-1952. doi: 10.1093/eurheartj/ehad093. PMID: 36932691; PMCID: PMC10232276.


Bojkova D, Reus P, Panosch L, Bechtel M, Rothenburger T, Kandler JD, Pfeiffer A, Wagner JUG, Shumliakivska M, Dimmeler S, Olmer R, Martin U, Vondran FWR, Toptan T, Rothweiler F, Zehner R, Rabenau HF, Osman KL, Pullan ST, Carroll MW, Stack R, Ciesek S, Wass MN, Michaelis M, Cinatl J Jr. Identification of novel antiviral drug candidates using an optimized SARS-CoV-2 phenotypic screening platform. iScience. 2023 Feb 17;26(2):105944. doi: 10.1016/j.isci.2023.105944. Epub 2023 Jan 7. PMID: 36644320; PMCID: PMC9822553.


Maegdefessel L, Boon RA, Dimmeler S. Noncoding RNAs in the Vasculature: Basic Mechanisms and Therapeutic Perspectives. Arterioscler Thromb Vasc Biol. 2024 Jan;44(1):3-6. doi: 10.1161/ATVBAHA.123.319564. Epub 2023 Dec 27. PMID: 38150514.


Aslan GS, Jaé N, Manavski Y, Fouani Y, Shumliakivska M, Kettenhausen L, Kirchhof L, Günther S, Fischer A, Luxán G, Dimmeler S. Malat1 deficiency prevents neonatal heart regeneration by inducing cardiomyocyte binucleation. JCI Insight. 2023 Mar 8;8(5):e162124. doi: 10.1172/jci.insight.162124. PMID: 36883566; PMCID: PMC10077484.


Zhu C, Baumgarten N, Wu M, Wang Y, Das AP, Kaur J, Ardakani FB, Duong TT, Pham MD, Duda M, Dimmeler S, Yuan T, Schulz MH, Krishnan J. CVD-associated SNPs with regulatory potential reveal novel non-coding disease genes. Hum Genomics. 2023 Jul 25;17(1):69. doi: 10.1186/s40246-023-00513-4. PMID: 37491351; PMCID: PMC10369730.


Glaser SF, Brezski A, Baumgarten N, Klangwart M, Heumüller AW, Maji RK, Leisegang MS, Guenther S, Zehendner CM, John D, Schulz MH, Zarnack K, Dimmeler S. Circular RNA circPLOD2 regulates pericyte function by targeting the transcription factor KLF4. Cell Rep. 2023 Aug 29;42(8):112824. doi: 10.1016/j.celrep.2023.112824. Epub 2023 Jul 22. PMID: 37481725.


Drenckhahn JD, Nicin L, Akhouaji S, Krück S, Blank AE, Schänzer A, Yörüker U, Jux C, Tombor L, Abplanalp W, John D, Zeiher AM, Dimmeler S, Rupp S. Cardiomyocyte hyperplasia and immaturity but not hypertrophy are characteristic features of patients with RASopathies. J Mol Cell Cardiol. 2023 May;178:22-35. doi: 10.1016/j.yjmcc.2023.03.003. Epub 2023 Mar 21. PMID: 36948385.


de Oliveira Freitas Machado C, Schafranek M, Brüggemann M, Hernández Cañás MC, Keller M, Di Liddo A, Brezski A, Blümel N, Arnold B, Bremm A, Wittig I, Jaé N, McNicoll F, Dimmeler S, Zarnack K, Müller-McNicoll M. Poison cassette exon splicing of SRSF6 regulates nuclear speckle dispersal and the response to hypoxia. Nucleic Acids Res. 2023 Jan 25;51(2):870-890. doi: 10.1093/nar/gkac1225. PMID: 36620874; PMCID: PMC9881134.


Warwick T, Buchmann GK, Pflüger-Müller B, Spaeth M, Schürmann C, Abplanalp W, Tombor L, John D, Weigert A, Leo-Hansmann M, Dimmeler S, Brandes RP. Acute injury to the mouse carotid artery provokes a distinct healing response. Front Physiol. 2023 Feb 7;14:1125864. doi: 10.3389/fphys.2023.1125864. PMID: 36824462; PMCID: PMC9941170.


Mas-Peiro S, Pergola G, Berkowitsch A, Meggendorfer M, Rieger MA, Vasa-Nicotera M, Dimmeler S, Zeiher AM. Long-term risk associated with clonal hematopoiesis in patients with severe aortic valve stenosis undergoing TAVR. Clin Res Cardiol. 2023 May;112(5):585-593. doi: 10.1007/s00392-022-02135-7. Epub 2023 Jan 21. PMID: 36680616; PMCID: PMC10160205.


Zhou Q, Boeckel JN, Yao J, Zhao J, Bai Y, Lv Y, Hu M, Meng D, Xie Y, Yu P, Xi P, Xu J, Zhang Y, Dimmeler S, Xiao J. Diagnosis of acute myocardial infarction using a combination of circulating circular RNA cZNF292 and clinical information based on machine learning. MedComm (2020). 2023 Jun 13;4(3):e299. doi: 10.1002/mco2.299. PMID: 37323876; PMCID: PMC10264944.


Hoffmann J, Hanß S, Kraus M, Schaller J, Schäfer C, Stahl D, Anker SD, Anton G, Bahls T, Blankenberg S, Blumentritt A, Boldt LH, Cordes S, Desch S, Doehner W, Dörr M, Edelmann F, Eitel I, Endres M, Engelhardt S, Erdmann J, Eulenburg K, Falk V, Felix SB, Frank D, Franke T, Frey N, Friede T, Geidel L, Germans L, Grabmaier U, Halle M, Hausleiter J, Jakobi V, Jebran AF, Jobs A, Kääb S, Karakas M, Katus HA, Klatt A, Knosalla C, Krebser J, Landmesser U, Lee M, Lehnert K, Lesser S, Leyh K, Lorbeer R, Mach-Kolb S, Meder B, Nagel E, Nolte CH, Parwani AS, Petersmann A, Puls M, Rau H, Reiser M, Rienhoff O, Scharfe T, Schattschneider M, Scheel H, Schnabel RB, Schuster A, Schmitt B, Seidler T, Seiffert M, Stähli BE, Stas A, J Stocker T, von Stülpnagel L, Thiele H, Wachter R, Wakili R, Weis T, Weitmann K, Wichmann HE, Wild P, Zeller T, Hoffmann W, Zeisberg EM, Zimmermann WH, Krefting D, Kühne T, Peters A, Hasenfuß G, Massberg S, Sommer T, Dimmeler S, Eschenhagen T, Nauck M. The DZHK research platform: maximisation of scientific value by enabling access to health data and biological samples collected in cardiovascular clinical studies. Clin Res Cardiol. 2023 Jul;112(7):923-941. doi: 10.1007/s00392-023-02177-5. Epub 2023 Mar 8. PMID: 36884078; PMCID: PMC10293401.

Speer T, Dimmeler S, Schunk SJ, Fliser D, Ridker PM. Targeting innate immunity-driven inflammation in CKD and cardiovascular disease. Nat Rev Nephrol. 2022 Dec;18(12):762-778. doi: 10.1038/s41581-022-00621-9. Epub 2022 Sep 5. PMID: 36064794.


Hua Y, Vella G, Rambow F, Allen E, Antoranz Martinez A, Duhamel M, Takeda A, Jalkanen S, Junius S, Smeets A, Nittner D, Dimmeler S, Hehlgans T, Liston A, Bosisio FM, Floris G, Laoui D, Hollmén M, Lambrechts D, Merchiers P, Marine JC, Schlenner S, Bergers G. Cancer immunotherapies transition endothelial cells into HEVs that generate TCF1+ T lymphocyte niches through a feed-forward loop. Cancer Cell. 2022 Dec 12;40(12):1600-1618.e10. doi: 10.1016/j.ccell.2022.11.002. Epub 2022 Nov 23. Erratum in: Cancer Cell. 2023 Jan 9;41(1):226. DOI: 10.1016/j.ccell.2022.11.002. PMID: 36423635; PMCID: PMC9899876. 


Luxán G, Dimmeler S. The vasculature: a therapeutic target in heart failure? Cardiovasc Res. 2022 Jan 7;118(1):53-64. doi: 10.1093/cvr/cvab047. PMID: 33620071; PMCID: PMC8752358.


Abplanalp WT, Merten M, Dimmeler S. Straight to the Heart: T Cells That Specifically Target Cardiac Tissue. Circulation. 2022 Dec 20;146(25):1946-1949. doi: 10.1161/CIRCULATIONAHA.122.061324. Epub 2022 Dec 19. PMID: 36534731.


Abplanalp WT, Tucker N, Dimmeler S. Single-cell technologies to decipher cardiovascular diseases. Eur Heart J. 2022 Nov 14;43(43):4536-4547. doi: 10.1093/eurheartj/ehac095. PMID: 35265972; PMCID: PMC9659476.


Tzahor E, Dimmeler S. A coalition to heal-the impact of the cardiac microenvironment. Science. 2022 Sep 2;377(6610):eabm4443. doi: 10.1126/science.abm4443. Epub 2022 Sep 2. PMID: 36048959.


Nicin L, Wagner JUG, Luxán G, Dimmeler S. Fibroblast-mediated intercellular crosstalk in the healthy and diseased heart. FEBS Lett. 2022 Mar;596(5):638-654. doi: 10.1002/1873-3468.14234. Epub 2021 Dec 1. PMID: 34787896.


Tombor LS, Dimmeler S. Why is endothelial resilience key to maintain cardiac health? Basic Res Cardiol. 2022 Jul 14;117(1):35. doi: 10.1007/s00395-022-00941-8. PMID: 35834003; PMCID: PMC9283358.


Fouani Y, Kirchhof L, Stanicek L, Luxán G, Heumüller AW, Knau A, Fischer A, Devraj K, John D, Neumann P, Bindereif A, Boon RA, Liebner S, Wittig I, Mogler C, Karimova M, Dimmeler S, Jaé N. The splicing-regulatory lncRNA NTRAS sustains vascular integrity. EMBO Rep. 2022 Jun 7;23(6):e54157. doi: 10.15252/embr.202154157. Epub 2022 May 8. PMID: 35527520; PMCID: PMC9171682.


Kokot KE, Kneuer JM, John D, Rebs S, Möbius-Winkler MN, Erbe S, Müller M, Andritschke M, Gaul S, Sheikh BN, Haas J, Thiele H, Müller OJ, Hille S, Leuschner F, Dimmeler S, Streckfuss-Bömeke K, Meder B, Laufs U, Boeckel JN. Reduction of A-to-I RNA editing in the failing human heart regulates formation of circular RNAs. Basic Res Cardiol. 2022 Jun 23;117(1):32. doi: 10.1007/s00395-022-00940-9. PMID: 35737129; PMCID: PMC9226085.


Cattaneo P, Hayes MGB, Baumgarten N, Hecker D, Peruzzo S, Aslan GS, Kunderfranco P, Larcher V, Zhang L, Contu R, Fonseca G, Spinozzi S, Chen J, Condorelli G, Dimmeler S, Schulz MH, Heinz S, Guimarães-Camboa N, Evans SM. DOT1L regulates chamber-specific transcriptional networks during cardiogenesis and mediates postnatal cell cycle withdrawal. Nat Commun. 2022 Dec 2;13(1):7444. doi: 10.1038/s41467-022-35070-2. PMID: 36460641; PMCID: PMC9718823.


Nicin L, Schroeter SM, Glaser SF, Schulze-Brüning R, Pham MD, Hille SS, Yekelchyk M, Kattih B, Abplanalp WT, Tombor L, Müller OJ, Braun T, Meder B, Reich C, Arsalan M, Holubec T, Walther T, Emrich F, Krishnan J, Zeiher AM, John D, Dimmeler S. A human cell atlas of the pressure-induced hypertrophic heart. Nat Cardiovasc Res. 2022 Feb;1(2):174-185. doi: 10.1038/s44161-022-00019-7. Epub 2022 Feb 14. PMID: 39195989; PMCID: PMC11357985.


Kuhnert S, Mansouri S, Rieger MA, Savai R, Avci E, Díaz-Piña G, Padmasekar M, Looso M, Hadzic S, Acker T, Klatt S, Wilhelm J, Fleming I, Sommer N, Weissmann N, Vogelmeier C, Bals R, Zeiher A, Dimmeler S, Seeger W, Pullamsetti SS. Association of Clonal Hematopoiesis of Indeterminate Potential with Inflammatory Gene Expression in Patients with COPD. Cells. 2022 Jul 5;11(13):2121. doi: 10.3390/cells11132121. PMID: 35805204; PMCID: PMC9265467.


Gimbel AT, Koziarek S, Theodorou K, Schulz JF, Stanicek L, Kremer V, Ali T, Günther S, Kumar S, Jo H, Hübner N, Maegdefessel L, Dimmeler S, van Heesch S, Boon RA. Aging-regulated TUG1 is dispensable for endothelial cell function. PLoS One. 2022 Sep 29;17(9):e0265160. doi: 10.1371/journal.pone.0265160. PMID: 36173935; PMCID: PMC9522302.


Heumüller AW, Jones AN, Mourão A, Klangwart M, Shi C, Wittig I, Fischer A, Muhly-Reinholz M, Buchmann GK, Dieterich C, Potente M, Braun T, Grote P, Jaé N, Sattler M, Dimmeler S. Locus-Conserved Circular RNA cZNF292 Controls Endothelial Cell Flow Responses. Circ Res. 2022 Jan 7;130(1):67-79. doi: 10.1161/CIRCRESAHA.121.320029. Epub 2021 Nov 18. PMID: 34789007.


Kirchhof L, Fouani Y, Knau A, Aslan GS, Heumüller AW, Wittig I, Müller-McNicoll M, Dimmeler S, Jaé N. The G3BP1-UPF1-Associated Long Non-Coding RNA CALA Regulates RNA Turnover in the Cytoplasm. Noncoding RNA. 2022 Jun 30;8(4):49. doi: 10.3390/ncrna8040049. PMID: 35893232; PMCID: PMC9326601.


Brüning RS, Tombor L, Schulz MH, Dimmeler S, John D. Comparative analysis of common alignment tools for single-cell RNA sequencing. Gigascience. 2022 Jan 27;11:giac001. doi: 10.1093/gigascience/giac001. PMID: 35084033; PMCID: PMC8848315.


Achenbach S, Fuchs F, Goncalves A, Kaiser-Albers C, Ali ZA, Bengel FM, Dimmeler S, Fayad ZA, Mebazaa A, Meder B, Narula J, Shah A, Sharma S, Voigt JU, Plein S. Non-invasive imaging as the cornerstone of cardiovascular precision medicine. Eur Heart J Cardiovasc Imaging. 2022 Mar 22;23(4):465-475. doi: 10.1093/ehjci/jeab287. PMID: 35048106; PMCID: PMC13376137.


de Boer RA, Heymans S, Backs J, Carrier L, Coats AJS, Dimmeler S, Eschenhagen T, Filippatos G, Gepstein L, Hulot JS, Knöll R, Kupatt C, Linke WA, Seidman CE, Tocchetti CG, van der Velden J, Walsh R, Seferovic PM, Thum T. Targeted therapies in genetic dilated and hypertrophic cardiomyopathies: from molecular mechanisms to therapeutic targets. A position paper from the Heart Failure Association (HFA) and the Working Group on Myocardial Function of the European Society of Cardiology (ESC). Eur J Heart Fail. 2022 Mar;24(3):406-420. doi: 10.1002/ejhf.2414. Epub 2022 Jan 14. PMID: 34969177; PMCID: PMC9305112.


Kattih B, Carstens DC, Boeckling F, Rasper T, Pergola G, Dimmeler S, Vasa-Nicotera M, Zeiher AM, Mas-Peiro S. Low Circulating Musclin is Associated With Adverse Prognosis in Patients Undergoing Transcatheter Aortic Valve Implantation at Low-Intermediate Risk. J Am Heart Assoc. 2022 Mar 15;11(6):e022792. doi: 10.1161/JAHA.121.022792. Epub 2022 Mar 1. PMID: 35229655; PMCID: PMC9075297.


Hoffmann J, Tabata N, Mas-Peiro S, Spyridopoulos I, Sinning JM, Berkowitsch A, Martin-Ruiz C, Al-Kassou B, Herrmann E, Dimmeler S, Zeiher AM, Vasa-Nicotera M. Longer leukocyte telomere length is associated with myeloid inflammation and increased mortality after transcatheter aortic valve replacement. Eur Heart J Open. 2022 Jul 23;2(4):oeac045. doi: 10.1093/ehjopen/oeac045. PMID: 35983406; PMCID: PMC9380992.


Lim OZH, Chen Y, Dimmeler S, Yong AWJ, Singh H, Sim MLE, Kong G, Lim WH, Low TT, Park DW, Chew NWS, Foo R. Disparity in female and Asian representation amongst cardiology journal editorial boards members: a call for empowerment. QJM. 2022 Dec 12;115(12):830-836. doi: 10.1093/qjmed/hcac176. PMID: 35866641.